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Authors
Mattos, Antônio José Cordeiro
Mazon, Francisco Jose Nigro
Theotonio dos Santos, Lucas Ferreira
Bianco, Juares Ednaldo Romero
Monfardini, Frederico
dos Santos, Gustavo Prado
de Sousa, Lívia Dias
Sasse, Mariana Martins
Rizzo, Luiz Vicente
Fonseca, Henrique Andrade R. https://orcid.org/0000-0001-8360-8465
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Funding
Funding for this research was provided by:
AstraZeneca (D7000R00020)
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Article History
Received: 26 January 2026
Accepted: 20 April 2026
First Online: 15 May 2026
Declarations
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: Antonio José Cordeiro Mattos, Francisco Jose Nigro Mazon, Henrique Andrade Rodrigues Fonseca, Frederico Monfardini, Gustavo Prado dos Santos, Lucas F. Theotonio dos Santos, and Luiz Vicente Rizzo received research grants (paid to the institution) by AstraZeneca. Juares Ednaldo Romero Bianco, Livia Dias de Sousa, and Mariana Martins Sasse report relationships with AstraZeneca that include employment and equity or stocks.
: The datasets were validated by removing duplicate entries and ensuring the consistency and completeness of the registered data, in compliance with the guidelines from the Research Ethics of the National Health Council, Brazil. Written informed consent was not required for participation in this study, in accordance with national legislation and institutional regulations. As this study was based on an analysis of publicly accessible and anonymized databases, the need for ethical approval was waived. The anonymized data guaranteed the safeguarding of sensitive information regarding individuals registered in the dataset.
