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Authors
Xie, Jin-Xi
Wang, Xue
Li, Yang
Zhang, Ye
Liu, Tao
Liu, Ming-Ming
Liu, Jun-Li
Zhou, Li-Wen https://orcid.org/0009-0002-1539-9088
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Clinical Trials BETA
Clinical trials referenced in this document:
chictr2300078997 at Chinese Clinical Trial RegistryDocuments that mention this clinical trial
Effect of Esketamine Combined with Lidocaine on Opioid Requirements in the Elderly Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized, Double-Blind, Controlled Trial
https://doi.org/10.1007/s40122-025-00809-4
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Funding
Funding for this research was provided by:
Chen Xiao-Ping Foundation for The Development of Science and Technology of Hubei Province (CXPJJH12000005-07-37)
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Article History
Received: 7 October 2025
Accepted: 8 December 2025
First Online: 22 December 2025
Declarations
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: Jin-Xi Xie reports financial support provided by Chen Xiao-Ping Foundation for The Development of Science and Technology of Hubei Province (CXPJJH12000005-07-37). The other authors (Xue Wang, Yang Li, Ye Zhang, Tao Liu, Ming-Ming Liu, Jun-Li Liu, and Li-Wen Zhou) declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
: This study was conducted in accordance with the ethical principles of the World Medical Association Declaration of Helsinki (1964) and its subsequent amendments. Formal ethical approval was obtained from the Ethics Committee of the Xiangyang Central Hospital, affiliated to Hubei University of Arts and Science on 9 November 2023 (approval no. 2023-114-02) and registered in the Chinese Clinical Trial Registry (registration no. ChiCTR2300078997). Prior to participation, written informed consent was obtained from all individual participants involved in the study. The consent process explicitly detailed the study’s purpose, procedures, potential risks and benefits, and the right to refuse or withdraw participation at any time without penalty. Furthermore, participants provided specific consent for the publication of anonymized data obtained from the research. All personally identifiable information has been removed to protect participant confidentiality.
