Jin, Zhousheng
Sun, Jiaying
Zha, Yujun
Ji, Shijie
Deng, Shikang
Qiang, Youmei
Chen, Hongfei
Funding for this research was provided by:
Basic Research Project of Wenzhou City (GK20250008)
Article History
Received: 10 July 2026
Accepted: 8 September 2026
First Online: 24 September 2026
Declarations
Conflict of Interest: Zhousheng Jin, Jiaying Sun, Yujun Zha, Shijie Ji, Shikang Deng, Youmei Qiang, and Hongfei Chen have nothing to disclose.
Ethical Approval: This single-center, prospective, randomized, single-blind, controlled trial has been approved by Ethics Committee in Clinical Research of the First Affiliated Hospital of Wenzhou Medical University (Approved No. of ethic committee: Clinical Research Ethics Review Issuing Number (2024) No. 171). All participants provided written informed consent. The study has been registered with the Chinese Clinical Trial Registry (The registry: The First Affiliated Hospital of Wenzhou Medical University. Registration number: ChiCTR2400092616. Principal investigator’s name: Hongfei Chen. Date of registration: 2024-11-20. ). This study was conducted in accordance with the Declaration of Helsinki.