Alves-Ambrósio, João https://orcid.org/0000-0003-2009-5126
Teixeira, Pedro Cardoso https://orcid.org/0000-0003-0253-5570
Garcia, Mariana
Chibante-Pedro, João
Ruão, Miguel https://orcid.org/0000-0002-0858-0164
Funding for this research was provided by:
Alimera Sciences
Article History
Received: 28 October 2025
Accepted: 31 October 2025
First Online: 14 November 2025
Declarations
:
: João Alves Ambrósio, Pedro Cardoso Teixeira, Mariana Garcia, João Chibante Pedro, and Miguel Ruão declare that they have no conflicts of interest relevant to this work.
: The study was approved by the Comissão de Ética para a Saúde da Unidade Local de Saúde Entre Douro e Vouga (approval number: CES 23_2023). All procedures adhered to the principles of Good Clinical Practice and the Declaration of Helsinki. Written informed consent was obtained from all participants before enrollment.