Lei, Chaoyu
Jin, Jun
Li, Runchuan
Yip, Chee Chew
Chong, Kelvin Kam Lung
Smith, Terry J.
Sun, Jing
Zhou, Huifang https://orcid.org/0000-0002-8636-861X
Funding for this research was provided by:
National Natural Science Foundation of China (82388101)
National Natural Science Foundation of China (82271122)
National Key R&D Program of China (2024YFB4710200)
National Key R&D Program of China (2024YFB4710205)
Hainan Province Science and Technology Special Fund (ZDYF2024LCLH004)
Science and Technology Commission of Shanghai Municipality (20DZ2270800)
Shanghai Key Clinical Specialty, Shanghai Eye Disease Research Center (2022ZZ01003)
Shanghai Municipal Commission of Health and Family Planning Project (2022XD006)
Shanghai Jiao Tong University 2030 Initiative (WH510272301)
Shanghai Three-Year Plan for the Inheritance and Innovative Development of Traditional Chinese Medicine (2-5-1)
Shanghai Jiao Tong University Hainan Institute's Independent Research Initiative (HRSJ-ZSZX-009)
Article History
Received: 26 November 2025
Accepted: 21 January 2026
First Online: 16 February 2026
Conflict of Interest
: Chaoyu Lei has nothing to disclose. Jun Jin has nothing to disclose. Runchuan Li has nothing to disclose. Chee Chew Yip has nothing to disclose. Kelvin Kam Lung Chong has nothing to disclose. Terry J. Smith was issued patents for targeting IGF-IR as therapy for autoimmune diseases, including TAO, held by Lundquist Institute/UCLA and University of Michigan; and serves as consultant, Amgen (formerly Horizon), Viridian Therapeutics, Lundbeck, Argenx, Lassen Therapeutics, Minghui Pharmaceuticals, Innovent Biologics, Bristol Myers Squibb, Arrowhead Pharma, Ollin Bioscience, and Escient Pharma. Jing Sun has nothing to disclose. Huifang Zhou has nothing to disclose.
: This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.