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Article History

Accepted: 22 August 2024

First Online: 18 October 2024

Declarations

:

: Open access funding provided by Technion - Israel Institute of Technology.

: May Hilu, Mariana Issawy, Raul Colodner, Harel Eitam, Gilat Ron Avraham, Kerstin Carlin Ram, Mazen Elias, Orli Shimoni, Eyal Schwartzberg, and Lee Hilary Goldstein have no relevant financial or non-financial interests to disclose.

: All authors contributed to the study conception and design. Material preparation and data collection and analysis were performed by MH, LHG, ES, KCR, and GRA. The first draft of the manuscript was written by MH. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. Author handling publication process: MI.

: This study was performed in line with the principles of the declaration of Helsinki. Approval was granted by the Ethics Committee of HaEmek Medical Center (number of NIH: NCT03893591; date of registration: May 2019).

: This study was approved by the local independent review board of HaEmek Medical Center, and informed consent was obtained from all individual participants included in the study.

: Consent for publication is not relevant to this study.

: The datasets generated and analyzed during the current study are not publicly available, but are available from the corresponding author on reasonable request.

: Not applicable.