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Article History

First Online: 27 January 2018

Compliance with Ethical Standards

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: Caitriona Ryan has acted as an advisor and/or speaker for AbbVie, Aqua, Dermira, Dr. Reddy’s, Janssen, Leo, Lilly, Medimetriks, Novartis, Regeneron-Sanofi, UCB, and Xenoport. Jeffrey M. Sobell has received honoraria and/or research funding from Amgen, AbbVie, Janssen, Celgene, Novartis, Lilly, Lycera, and Merck. Craig L. Leonardi has received funding from AbbVie, Actavis, Amgen, Celgene, Coherus, Dermira, Eli Lilly, Galderma, Janssen, Leo, Merck, Novartis, Pfizer, Sandoz, Stiefel, UCB, and Wyeth. Charles W. Lynde has received funding from AbbVie, Amgen, Boehringer, Celgene, Coherus, Dermira, Eli Lilly, Galderma, Innovaderm, Janssen, Leo Pharma, Merck, MSD, MedImmune, Novartis, Pfizer, Regeneron, and Xoma and reimbursement of traveling, accommodation, and hospitality expenses from AbbVie, Amgen, Boehringer, Celgene, Eli Lilly, Janssen, Leo Pharma, Merck, MSD, Novartis, Pfizer, and Valeant. Wendell C. Valdecantos and Barbara A. Hendrickson are employees of AbbVie, Inc. and may own AbbVie stock and/or stock options. Mahinda Karunaratne was an employee of AbbVie, Inc. at the time of this research and may own AbbVie stock and/or stock options.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

: Informed consent was obtained from all participants in the individual studies included in these analyses.