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Article History

Accepted: 19 October 2020

First Online: 18 February 2021

Declarations

:

: Trials were supported by Verrica Pharmaceuticals Inc.

: Lawrence F. Eichenfield, MD, received funds for research to his institution as a study center and consulting fees and stock options from Verrica Pharmaceuticals Inc. He is also on the board of directors for Verrica Pharmaceuticals Inc. Elaine Siegfried, MD, received funds for research to her institution as a study center and consulting fees from Verrica Pharmaceuticals Inc. She has also received consulting fees and funds as a research center for Novan. Pearl Kwong, MD, received funds for research as a study center and consulting fees from Verrica Pharmaceuticals Inc. Mark McBride, PhD, was paid as a consultant to run analyses on the statistics for the study by Verrica Pharmaceuticals Inc. Dr. McBride is also a consultant for Novan. Jayson Rieger, PhD, was an employee of Verrica Pharmaceuticals, holds company stock from Verrica Pharmaceuticals Inc., and holds a patent related to the work. David Glover, PhD, is an employee of PBM Capital Group. Cynthia Willson, RN, BSN, is an employee of Verrica Pharmaceuticals and holds company stock. Matthew Davidson, PhD, was an employee of, received personal fees from, and holds stock of Verrica Pharmaceuticals Inc. He also holds patents related to the research. Patrick Burnett, MD, PhD, was an employee of Verrica Pharmaceuticals and holds company stock. Melissa Olivadoti, PhD, is an employee of Verrica Pharmaceuticals.

: Not applicable.

: Not applicable.

: Conceptualization: MD, JR, ES, CW, DG. Methodology: MD, JR, MM, DG. Formal analysis and investigation: MD, JR, MM, PB, CW, LE, ES, PK. Writing—original draft preparation: MO. Writing—review and editing: JR, MD, MM, PB, CW, LE, ES, PK, DG, MO. Funding acquisition: JR, MD. Supervision: PB, CW, JR, DG, MD.

: Local institutional review boards or ethics committees at each trial center approved the protocol and consent form, oversaw trial conduct, and maintained documentation.

: Written informed consent was obtained from the 17 adult participants and the parents or guardians of participants aged < 18 years as per the local state regulations.

: Not applicable as no patient-related data were used.