Garcia-Huidobro, Diego http://orcid.org/0000-0003-1964-7640
Iturriaga, Carolina
Perez-Mateluna, Guillermo
Fajuri, Paula
Severino, Nicolás
Urzúa, Marcela
Fraga, Juan Pablo
de la Cruz, Javiera
Poli, Cecilia
Castro-Rodríguez, José A.
Fish, Eleanor
Borzutzky, Arturo
Pablo Olivo, Juan
Suisbert, Katherine
Cruz, Andrea
Perez, Katterine
Valdivieso, Romina
Navarro, Diego
Pereira, Francisco
Monge, Vanessa
Dibarrart, Marisol
Salazar, Krisbeth
Bracho, Morgan
Pontanilla, Lidia
,
Funding for this research was provided by:
Altum Pharmaceuticals
Article History
Accepted: 28 May 2023
First Online: 22 June 2023
Declarations
:
: This study was funded by Altum Pharmaceuticals Inc., Vancouver, BC, Canada.
: Diego Garcia-Huidobro, Carolina Iturriaga, Guillermo Perez-Mateluna, Paula Fajuri, Nicolás Severino, Marcela Urzúa, Juan Pablo Fraga, Javiera de la Cruz, Cecilia Poli, José A. Castro-Rodríguez, Eleanor Fish, and Arturo Borzutzky have no conflicts of interest that are directly relevant to the content of this article.
: All procedures in this study were in accordance with the 1964 Helsinki Declaration (and its amendments) and were approved by the Pontificia Universidad Católica de Chile Scientific Ethics Committee (approval #210224003).
: All participants were informed about the study and provided written consent to participate.
: All participants provided consent to use their data in publications.
: The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available because of privacy restrictions.
: Not applicable.
: All authors contributed to the study design and/or implementation. The study protocol was designed by AB, CI, DG-H, EF, and JAC-R. Material preparation was performed by CI, PF, MU, and AB. Participant recruitment and data collection procedures were supervised by PF and MU. Laboratory samples and analyses were processed by GP-M and JPF. JdlC and CP conducted the interferon gene signature analyses. NS oversaw the drug storage and administration. Data analyses were conducted by DG-H, JdlC, and AB. The first draft of the manuscript was written by DG-H and all authors commented and reviewed subsequent versions of the manuscript. All authors read and approved the final manuscript.