Updates are available Correction dated 2025-06-04

Article History

Accepted: 15 April 2025

First Online: 30 April 2025

Change Date: 4 June 2025

Change Type: Update

Change Details: The original online version of this article was revised due to a retrospective Open Access cancellation

Change Date: 4 June 2025

Change Type: Correction

Change Details: A Correction to this paper has been published:

Change Details: https://doi.org/10.1007/s40261-025-01452-9

Declarations

:

: The project was funded by the Innovation for All scheme of Cardiff University and Wellcome Trust (WT109455MA). The funding bodies had no role in the study’s design, data collection, analysis, interpretation, and manuscript writing.

: S.P. and P.P. are named inventors on a patent related to the use of PBAE for enhanced drug delivery in cartilage. S.S. has no conflicts to declare.

: Ethical approval for the research (SREC reference 2122-08a) was granted by the Cardiff School of Pharmacy and Pharmaceutical Sciences Research Ethics Committee. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

: All participants gave written informed consent for participation in the study.

: Participants agreed for aggregated data to be published.

: Please reach out to the corresponding author for microsimulation code.

: Data archiving is not mandated but anonymised and will be made available on reasonable request. All data on costs and utilities are from publicly available resources.

: P.P. acquired funding, conceptualised the study, project management, and reviewed the draft. S.P. developed the economic analysis, data analysis, and drafted the manuscript. S.S. carried out the survey and data analysis. All authors read and approved the final version and agree to be accountable for the work.