Hornik, Christoph P.
Wu, Huali
Edginton, Andrea N.
Watt, Kevin
Cohen-Wolkowiez, Michael
Gonzalez, Daniel
Funding for this research was provided by:
National Institutes of Health (1R01-HD076676-01A1)
Article History
First Online: 13 March 2017
Compliance with Ethical Standards
:
: This work was funded by the National Institutes of Health (1R01-HD076676-01A1; MCW).
: Christoph P. Hornik receives salary support for research from the National Center for Advancing Translational Sciences of the National Institutes of Health (UL1TR001117) and the US government for his work in pediatric and neonatal clinical pharmacology (Government Contract HHSN267200700051C, PI: Benjamin under the Best Pharmaceuticals for Children Act). Andrea N. Edginton receives support for research from the National Institutes of Health (1R01-HD076676-01A1; PI: Cohen-Wolkowiez). Kevin Watt receives support from the Pediatric Critical Care and Trauma Scientist Development Program (5K12HD047349) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD; 1K23HD075891, 2K24HD058735). Michael Cohen-Wolkowiez receives support for research from the National Institutes of Health (1R01-HD076676-01A1), the National Institute of Allergy and Infectious Diseases (HHSN272201500006I and HHSN272201300017I), the National Institute of Child Health and Human Development (HHSN275201000003I), the Biomedical Advanced Research and Development Authority (HHSO100201300009C), and industry for drug development in adults and children (ExternalRef removed). Daniel Gonzalez receives support for research from the NICHD (K23HD083465), the nonprofit organization Thrasher Research Fund (ExternalRef removed), and from industry (Cempra, Inc. and Jacobus Pharmaceutical Company, Inc.) for drug development in adults and children. Huali Wu has no conflicts of interest to declare. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
: Clinical PK data used in this publication were collected during the POP01 clinical trial (ClinicalTrials.gov identifier: NCT01431326). The POP01 study protocol was reviewed and approved by the Institutional Review Board of each participating institution.
: Informed consent and assent, when applicable, was obtained from all participants enrolled in the POP01 clinical trial who contributed clinical PK data used in this study.