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Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults

Crossref DOI link: https://doi.org/10.1007/s40262-019-00737-5

Published Online: 2019-02-15

Published Print: 2019-07-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Guo-Fu https://orcid.org/0000-0002-4628-9941
Zheng, Qing-Shan

Yu, Yichao

Zhong, Wei

Zhou, Hong-Hao

Qiu, Furong

Wang, Guangji

Yu, Guo

Derendorf, Hartmut
Funding

Funding for this research was provided by:

Young Scientists Fund (81603209)

Six Talent Peaks Project in Jiangsu Province (No. 2015-WSN-111)
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Version of Record valid from 2019-02-15
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Article History

First Online: 15 February 2019

Compliance with Ethical Standards

:

: This study was supported by in part by the National Natural Science Foundation of China (no. 81603209) and the Six Talent Peaks Project in Jiangsu Province (no. 2015-WSN-111). These research grants were received by G.Y. The funding organizations played no role in the preparation, review, or approval of the manuscript.

: Guo-Fu Li, Qing-Shan Zheng, Yichao Yu, Wei Zhong, Hong-Hao Zhou, Furong Qiu, Guangji Wang, Guo Yu, and Hartmut Derendorf have no conflicts of interest that are directly relevant to the contents of this manuscript.

: Not applicable.

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