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Article History

Accepted: 16 October 2020

First Online: 15 February 2021

Declarations

:

: The DIAMOND trial was funded by Astra Zeneca.

: Annemarie B. van der Aart-van der Beek, Abdul Halim Abdul Gafor, Claire C.J. Dekkers, Daniel C. Cattran, Jasper Stevens, Jeroen V. Koomen, Qiang Li, Sean J. Barbour and Sunita Singh have no conflicts of interest that are directly relevant to the content of this article. Hiddo J.L. Heerspink is a consultant to Abbvie, AstraZeneca, Boehringer Ingelheim, Bayer, Chinook, CSL Behring, Gilead, Janssen, Merck, Mundipharma, Mitsubishi Tanabe, Novo Nordisk and Retrophin. He received research support from AstraZeneca, Abbvie, Boehringer Ingelheim and Janssen. David W. Boulton is an employee and shareholder of AstraZeneca. David Z.I. Cherney has received honoraria from Boehringer Ingelheim-Lilly, Merck, AstraZeneca, Sanofi, Mitsubishi-Tanabe, Abbvie, Janssen, Bayer, Prometic, BMS and Novo-Nordisk and has received operational funding for clinical trials from Boehringer Ingelheim-Lilly, Merck, Janssen, Sanofi, AstraZeneca and Novo-Nordisk. Ron T. Gansevoort has consulting agreements with AstraZeneca, Bayer, Sanofi-Genzyme and Mundi Pharma; all fees are paid to his institution. Peter J. Greasley is employed by and owns shares in AstraZeneca. Gozewijn D. Laverman has received research grants and consulting fees from Sanofi and AstraZeneca, and research grants from Novo Nordisk. Marc G. Vervloet has received consulting fees from Amgen, Vifor, Fresenius Medical Care Renal Pharma, Medice, Kyowa Kirin and Astra Zeneca. Heather N. Reich has received consulting fees from Omeros and was involved in clinical trials supported by Omeros and Calliditas. Soo Kun Lim has received consulting fees or speaking honoraria from AstraZeneca, Boehringer Ingelheim, Novo Nordisk, Fresenius Kabi, Baxter and Sanofi.

: JVK analysed the data. ABvdAB, JVK and HJLH wrote the manuscript. Other authors revised the draft manuscript for important intellectual content. All authors contributed to the data collection and all authors approved the manuscript for submission.

: The DIAMOND studie was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committees of each participating center.

: All DIAMOND participants provided written informed consent.

: All authors approved and provied consent for publication.

: The datasets generated during and/or analysed during the curret study are available from the corresponding author on reasonable request.

: Not applicable.