Bukkems, V. E. http://orcid.org/0000-0002-7644-1123
van Hove, H.
Roelofsen, D.
Freriksen, J. J. M.
van Ewijk-Beneken Kolmer, E. W. J.
Burger, D. M.
van Drongelen, J.
Svensson, E. M.
Greupink, R.
Colbers, A.
Funding for this research was provided by:
Merck Sharp and Dohme (Recipient: David Burger)
Article History
Accepted: 4 April 2022
First Online: 17 May 2022
Declarations
:
: The institution received funding from Merck Sharp & Dohme Corp to perform the ex vivo human placenta perfusion experiments.
: AC has received honoraria from Merck Sharp & Dohme Corp 2021, paid to their institution. A Colbers and D Burger have received study grants from Merck Sharp & Dohme Corp, Gilead, and ViiV Healthcare, paid to their institution. VE Bukkems, H van Hove, D Roelofsen, JJM Freriksen, EWJ van Ewijk-Beneken Kolmer, J van Drongelen, EM Svensson, and R Greupink have no conflicts of interest that are directly relevant to the content of this article.
: Data are stored at the Deparment of Pharmacy and the Deparment of Pharmaclogy-Toxicology of the Radboud University Medical Center. Data may be available upon request to the authors.
: For performing the placenta perfusion experiments, the regional institutional medical ethical committee provided a waiver for formal approval based on the Dutch Law for Human research (CMO Arnhem/Nijmegen File 2014-1397).
: Informed consent was obtained from the women who donated their placentas for the placenta perfusing experiments.
: V E Bukkems, H van Hove, D Roelofsen, J J M Freriksen, D Burger, J van Drongelen, R Greupink, and A Colbers designed the research. V E Bukkems, H van Hove, and D Roelofsen performed the research. V E Bukkems, H van Hove, D Roelofsen, J J M Freriksen, E W J van Ewijk-Beneken Kolmer, E Svensson, R Greupink, and A Colbers analyzed the data. V E Bukkems, H van Hove, and D Roelofsen wrote the manuscript.