Zhang, Tan http://orcid.org/0000-0001-9355-2370
Krekels, Elke H. J. http://orcid.org/0000-0001-6006-1567
Smit, Cornelis http://orcid.org/0000-0002-1357-9248
van Dongen, Eric P. A.
Brüggemann, Roger J. M. http://orcid.org/0000-0002-7618-725X
Knibbe, Catherijne A. J. http://orcid.org/0000-0001-9893-4415
Clinical trials referenced in this document:
Documents that mention this clinical trial
How to Dose Vancomycin in Overweight and Obese Patients with Varying Renal (Dys)function in the Novel Era of AUC 400–600 mg·h/L-Targeted Dosing
https://doi.org/10.1007/s40262-023-01324-5
Funding for this research was provided by:
China Scholarship Council (201906010328)
ZonMw (836041004)
Article History
Accepted: 27 October 2023
First Online: 16 November 2023
Declarations
:
: The work of Tan Zhang was supported by the China Scholarship Council (201906010328). The AMIGO trial was funded by institutional research from The Netherlands Organization for Health Research and Development (ZonMW, 836041004).
: No disclosures are applicable for this work. Disclosures outside of this work: RJMB has served as consultants to Astellas Pharma, Inc., F2G, Amplyx, Gilead Sciences, Merck Sharp & Dohme Corp., and Pfizer, Inc., and has received unrestricted and research grants from Astellas Pharma, Inc., Gilead Sciences, Merck Sharp & Dohme Corp., and Pfizer, Inc. All contracts were through Radboudumc, and all payments were invoiced by Radboudumc. None of the other authors have any conflicts to declare.
: Data are available from the corresponding author upon request.
: For the study that was conducted during routine clinical care in the hospital, the Institutional Review Board (IRB) approved the protocol and waived the requirement of informed consent. The AMIGO trial was approved by the local human research and ethics committee (registered in the Dutch Trial Registry, NTR6058). All studies were conducted in accordance with the Declaration of Helsinki and the International Conference on Harmonization Guidelines in Good Clinical Practice.
: Written, informed consent was obtained from all participants in the AMIGO trial.
: Not applicable.
: The final model code will be made available in the DDMoRe model repository (ExternalRef removed).
: Conception and design of the research: TZ, EHJK, CS, and CAJK; data collection: CS and EPAD; data analysis: TZ; interpretation of findings: TZ, EHJK, CS, EPAD, RJMB, and CAJK; drafting the manuscript: TZ; critical revision of manuscript: EHJK, CS, EPAD, RJMB, and CAJK. All authors provided final manuscript approval.