van Borselen, Marjolein D. http://orcid.org/0000-0002-2547-9332
Sluijterman, Laurens Auke Æmiel http://orcid.org/0000-0001-6964-6481
Greupink, Rick http://orcid.org/0000-0003-2599-7540
de Wildt, Saskia N. http://orcid.org/0000-0002-0502-0647
Funding for this research was provided by:
Radboud Universitair Medisch Centrum
Bill and Melinda Gates Foundation
Article History
Accepted: 30 October 2023
First Online: 15 February 2024
Declarations
:
: Marjolein D. van Borselen is supported by a PhD grant of Radboudumc. Rick Greupink and Saskia N. de Wildt report receiving grants from the Bill and Melinda Gates Foundation outside the submitted work. The authors confirm independence from the sponsors; the content of the article has not been influenced by the sponsors.
: Marjolein D. van Borselen, Laurens Auke Æmiel Sluijterman, Rick Greupink, and Saskia N. de Wildt have no conflicts of interest that are directly relevant to the content of this article. Saskia N. de Wildt reported receiving data safety monitoring board membership fees from Khondrion paid to Radboud University Medical Center. No other disclosures were reported.
: Not applicable.
: Not applicable.
: Not applicable.
: The data analyzed during the current study are available from the corresponding author on reasonable request.
: The code utilized in this article for the software tool is available on GitHub: ExternalRef removed.
: All authors contributed to the writing of the manuscript. MB, LS, and RG designed the research. MB and LS performed the research. MB performed the PBPK modeling. LS contributed the analytical tool and statistics.