Carreño, Fernando O. http://orcid.org/0000-0002-4921-5235
Gerhart, Jacqueline G. http://orcid.org/0000-0003-4679-4638
Helfer, Victória E. http://orcid.org/0000-0002-6681-9356
Sinha, Jaydeep http://orcid.org/0000-0002-2110-3370
Kumar, Karan R. http://orcid.org/0000-0001-9196-6350
Kirkpatrick, Carl http://orcid.org/0000-0002-5715-1534
Hornik, Christoph P. http://orcid.org/0000-0001-7056-8759
Gonzalez, Daniel http://orcid.org/0000-0001-5522-5686
Benjamin, Daniel K. Jr.
Zimmerman, Kanecia
Kennel, Phyllis
Alderman, Cheryl
Sund, Zoe
Opel, Kylie
Beci, Rose
Hornik, Chi Dang
Kearns, Gregory L.
Laughon, Matthew
Paul, Ian M.
Sullivan, Janice
Wade, Kelly
Delmore, Paula
West, Leanne
Abdel-Rahman, Susan
Anand, Ravinder
Payne, Elizabeth
Chen, Lily
Simone, Gina
O’Connor, Kathleen
Cermak, Jennifer
Taylor, Lawrence
Green, Thomas
Benjamin, Danny
Taylor-Zapata, Perdita
Wade, Kelly
Kearns, Greg
Anand, Ravinder
Paul, Ian
Autmizguine, Julie
Capparelli, Edmund
Zimmerman, Kanecia
Greenberg, Rachel
Alderman, Cheryl
Green, Terren
Atz, Andrew
Lenert, Leslie
Clark, John
Chundru, Kalyan
Bendel, Catherine
Harvey, Brian
Grillo, Sonya
Chan, Francis
Fan, Stephanie
Downes, Kevin
Grundmeier, Robert
Ramos, Mark
O’Connor, Shawn
Fogel, Benjamin
Gipson, Debbie
Attala, Samara
Eickstadt, Richard
Kaleba, Erin
Liamini, Don
Estill, Jamie
Jared, Jeremy
Bow, Peter
Laughon, Matt
Talbert, Jennifer
Clark, Cindy
Miller, Michael
Muller, William
Smith, Michael
Sullivan, Janice
Heilman, Steve
Singh, K. P.
Vuyyuri, Satish
Schwitters, Jeff
Stone, Don
,
Funding for this research was provided by:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (5R01HD096435, HHSN275201000003I)
Article History
Accepted: 26 May 2024
First Online: 2 July 2024
Declarations
:
: This research was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under award 5R01HD096435. The enoxaparin pediatric data were collected by the Pediatric Trials Network (PTN) through NICHD contract HHSN275201000003I (Principal Investigator (PI): Daniel K. Benjamin, Jr.). F.O.C. and V.E.H. were supported through a University of North Carolina at Chapel Hill/GlaxoSmithKline (GSK) Pharmacokinetics/Pharmacodynamics Fellowship. J.G.G. received research support from a National Institute of General Medical Sciences (NIGMS) funded T32 program (T32GM122741), a Fred Eshelman Pre-Doctoral Fellowship in Pharmaceutical Sciences from the American Foundation for Pharmaceutical Education (AFPE), and a PharmAlliance travel award. D.G. received research support from the NICHD (5R01HD096435 and 1R01HD102949). The content is solely the authors’ responsibility and does not necessarily represent the official views of the National Institutes of Health.
: V.E.H.’s affiliation with GSK did not present any conflict of interest regarding the research, findings, or conclusions presented in this manuscript. The other authors have no relevant conflicts of interest to disclose. The work conducted and reported herein is free from any financial or personal relationships that could potentially bias the results or interpretations.
: To help expand the knowledge base for pediatric medicine, the PTN is pleased to share data from its completed and published studies with interested investigators. For requests, please contact PTN-Program-Manager@dm.duke.edu.
: The Institutional Review Board approved the protocol for this retrospective cohort study at Duke University (as the coordinating center) and all participating sites.
: A waiver of informed consent was granted by the Institutional Review Board.
: Not applicable.
: NONMEM control stream code for the final model is available as Electronic Supplementary Material.
: Performed the research: F.O.C., J.G.G., J.S., K.K., C.H., and D.G. Participated in research design: F.O.C., J.G.G., J.S., K.K., C.H., and D.G. Performed the data analysis: F.O.C., J.G.G., and V.E.H. Wrote or contributed to the writing of the manuscript: F.O.C., J.G.G., V.E.H., J.S., K.K., C.K., C.H., and D.G.