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Intrasubject Variability in Intravenous and Oral Probes for Hepatic and First-Pass CYP3A Activity

Published Online: 2024-07-29

Published Print: 2024-08

Authors

Kharasch, Evan D. https://orcid.org/0000-0002-6613-922X
Hoffer, Christine

Bedynek, Pamela
Funding

Funding for this research was provided by:

National Institutes of Health (R01-GM63674, R01-DA14211, K24-DA00417)
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Text and Data Mining valid from 2024-07-29

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Article History

Accepted: 16 July 2024

First Online: 29 July 2024

Declarations

:

: Supported by NIH grants R01-GM63674, R01-DA14211, and K24-DA00417 (EDK), and by M01-RR00037, provided to the University of Washington General Clinical Research Center.

: Evan D. Kharasch, Christine Hoffer, and Pamela Bedynek declare that they have no potential conflicts of interest that might be relevant to the contents of this article.

: Study conception and design and supervision: EDK. Data collection and patient management: CH. Analytical: PB. Data analysis: EDK. Manuscript writing, revision, and approval: EDK, CH, PB.

: The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

: The study protocol was approved by the University of Washington Institutional Review Board Ethics Committee, approval number HSRC 004540A01.

: Written, informed consent was obtained from all trial participants.

: Not applicable.

: Not applicable.

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