Hoffert, Yannick https://orcid.org/0000-0002-1631-9484
Dia, Nada https://orcid.org/0000-0003-1818-1949
Vanuytsel, Tim https://orcid.org/0000-0001-8728-0903
Vos, Robin https://orcid.org/0000-0002-3468-9251
Kuypers, Dirk https://orcid.org/0000-0001-5546-9680
Van Cleemput, Johan https://orcid.org/0000-0001-9246-6382
Verbeek, Jef https://orcid.org/0000-0002-1549-8003
Dreesen, Erwin https://orcid.org/0000-0002-0785-2930
Funding for this research was provided by:
Research Foundation Flanders (1SHAA24N, 1803521N, 1830517N)
Article History
Accepted: 12 August 2024
First Online: 20 September 2024
Change Date: 26 October 2024
Change Type: Update
Change Details: The original online version of this article was revised to correct a sentence beginning ‘The two-compartmental heart model…’.
Change Date: 24 October 2024
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1007/s40262-024-01438-4
Declarations
:
: Yannick Hoffert (1SHAA24N) is supported by a doctoral research grant from the Research Foundation - Flanders (FWO), Belgium. Robin Vos (1803521N) and Tim Vanuytsel (1830517N) are supported by the Research Foundation - Flanders (FWO), Belgium, as Senior Clinical Research Fellows.
: Tim Vanuytsel has given scientific advice to VectivBio, Shire, Dr. Falk Pharma, Takeda, and Baxter; has received research support from Danone, MyHealth, and VectivBio; and has served on the speaker bureau for Abbott, Tramedico, Truvion, Will Pharma, My Health, Kyowa Kirin, Menarini, Biocodex, Remedus, Fresenius Kabi, and Dr. Falk Pharma. Robin Vos received consultancy fees from AstraZeneca, GlaxoSmithKline, Takeda, Shionogi, and Zambon. Dirk Kuypers has received financial support from Astellas, Chiesi, and HIKMA. Jef Verbeek has received consultancy fees from Astellas. Erwin Dreesen has received consultancy fees from Alimentiv and Argenx, lecture fees from Galapagos and Celltrion, and financial support from Janssen, Prometheus, and Sandoz, outside the submitted work, with all honoraria/fees being paid to KU Leuven and not to any personal account of Erwin Dreesen. All authors have no conflicts of interest that are directly relevant to the content of this article.
: Not applicable.
: Not applicable.
: Not applicable.
: Not applicable.
: The model code that supports the findings of this study is available from the corresponding author upon reasonable request.
: Conceptualization: YH and ED; data curation: YH; formal analysis: YH; funding acquisition: YH; investigation: YH; methodology: YH and ED; project administration: YH and ED; resources: ED; software: YH; supervision: ED; validation: ND, TV, RV, DK, JVC, and JV; visualization: YH; writing—original draft: YH; writing—review and editing: YH, ND, TV, RV, DK, JVC, JV, and ED.