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Article History

Accepted: 4 December 2024

First Online: 11 February 2025

Declarations

:

: The clinical data employed in this study were obtained in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards (EudraCT number: 2019-003065-17).

: Informed consent was obtained from all participants included in the study.

: All the personal information susceptible to identifying individuals involved in the clinical trial was removed. Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.

: The authors declare that all the data supporting this study's findings are available within the paper and its Supplemental Data. More information can be provided on demand.

: The study was conducted without external funding.

: None of the authors reports any conflict of interest regarding this study.

: Participated in research design: Agustos C. Ozbey Neil Parrott, Kenichi Umehara, Georgina Meneses-Lorente. Performed Data Analysis: Agustos C. Ozbey, Kenichi Umehara. Wrote or Contributed to the Writing of the Manuscript: Agustos C. Ozbey, Pieter Annaert, Neil Parrott, Kenichi Umehara, Georgina Meneses-Lorente.