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Authors
Goutelle, Sylvain https://orcid.org/0000-0002-1853-2932
Bahuaud, Olivier
Genestet, Charlotte
Millet, Aurélien
Parant, François
Dumitrescu, Oana
Ader, Florence
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Ader, F.
Bahuaud, O.
Bayaa, R.
Becker, A.
Braun, E.
Chabert, P.
Chauvelot, P.
Chedid, C.
Conrad, A.
Dumitrescu, O.
Ferry, T.
Genestet, C.
Goutelle, S.
Hodille, E.
Hoffmann, J.
Javaux, C.
Lina, G.
Pouderoux, C.
Perpoint, T.
Roux, S.
Simon, M.
Valour, F.
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Funding
Funding for this research was provided by:
Agence Nationale de la Recherche (ANR-18-CE17-0020)
Hospices Civils de Lyon
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Article History
Accepted: 13 January 2025
First Online: 27 January 2025
Declarations
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: Open access funding provided by Hospices Civils de Lyon. This study was supported by a grant from the French National Research Agency (Agence Nationale pour la Recherche, ANR) [project PRIM-TB, ANR-18-CE17-0020].
: Sylvain Goutelle, Olivier Bahuaud, Charlotte Genestet, Aurélien Millet, François Parant, Oana Dumitrescu and Florence Ader have no conflicts of interest that are directly relevant to the content of this article.
: This study was approved by our institutional ethics committee (n°69HCL18_0757) and has been registered in the ClinicalTrials.gov website (NCT04271397).
: Written informed consent was obtained from all participants.
: Not applicable.
: The study data are available from the corresponding authors upon reasonable request.
: Not applicable.
: OD and FA initiated the project and designed the Opti-4TB trial. OB, OD and FA participated in the clinical data acquisition. CG, AM and FP participated in the collection of biological data. SG performed the PK data analysis and drafted the manuscript. All authors performed a critical review of the manuscript draft and approved the final version of the manuscript.
