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Article History

Accepted: 19 May 2025

First Online: 5 June 2025

Change Date: 7 January 2026

Change Type: Update

Change Details: This article was originally published under the subscription model but it is now published under an Open Access license.

Declarations

:

: The authors declare that they have no competing interests.

: Conceptualization—Benedict Morath, Kathrin I. Foerster, David Czock, Marcin Zaradzki, Matthias Karck, Walter E. Haefeli, and Sebastian G. Wicha; methodology—Benedict Morath, Ute Chiriac, Jürgen Burhenne, and Sebastian G. Wicha; formal analysis and investigation—Benedict Morath, Kathrin I. Foerster, Ute Chiriac, Jürgen Burhenne, Torsten Hoppe-Tichy, David Schrey, and Sebastian G. Wicha; Writing—original draft preparation—Benedict Morath, Ute Chiriac, and Sebastian G. Wicha; writing—review and editing—Benedict Morath, Kathrin I. Foerster, Ute Chiriac, Marcin Zaradzki, Torsten Hoppe-Tichy, David Schrey, Jürgen Burhenne, David Czock, Matthias Karck, Walter E. Haefeli, and Sebastian G. Wicha; resources—Torsten Hoppe-Tichy, Matthias Karck, and Walter E. Haefeli; supervision—Walter E. Haefeli and Sebastian G. Wicha.

: The authors declare that they have no financial interests.

: Open access funding enabled and organized by Projekt DEAL.

: Data are available upon reasonable request.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. A positive vote of the Ethics Committee of the Medical Faculty of Heidelberg University was obtained before the start of the study (S-523/2021).

: Informed consent was obtained from all individual participants included in the study.