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Article History

Accepted: 25 May 2025

First Online: 3 July 2025

Declarations

:

: This work was funded by the Swiss National Science Foundation, under grant IZSTZ0_208544.

: The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. Jan-Willem Alffenaar is an Editorial Board member of Clinical Pharmacokinetics. Jan-Willem Alffenaar was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions.

: Not applicable (NA).

: Not applicable.

: All authors consented on this publication.

: Data were extracted to Microsoft Excel spreadsheets and processed there. The data are available on request from the corresponding author.

: The code used for data analysis is available from the corresponding author upon reasonable request.

: “Conceptualisation, B.S. and S.M.; Drafting of the Protocol, BS.; search strings development and the literature search B.S., and Y.P.; Screening and data extraction B.S., P.H. and Y.P.; formal analysis, B.S.; data curation, Y.P. and P.H.; writing- original draft preparation, B.S.; writing- review and editing, B.S., P.H., Y.P., M.G., Y.T., V.K., M.S., S.K., J.-W. A, E.M., and S.M.; supervision S.M. and E.M.; funding acquisition, Y.T., M.G. and S.M. All authors have read and agreed to the published version of the manuscript”.