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Authors
Mueller, Lorenz https://orcid.org/0000-0002-9155-1080
Klaiber, Aaron https://orcid.org/0009-0004-5199-7004
Ley, Laura https://orcid.org/0009-0003-9881-4693
Becker, Anna M. https://orcid.org/0000-0001-5308-7945
Thomann, Jan https://orcid.org/0000-0003-3820-2671
Luethi, Dino https://orcid.org/0000-0003-0874-4875
Schmid, Yasmin https://orcid.org/0000-0002-3618-584X
Liechti, Matthias E. https://orcid.org/0000-0002-1765-9659
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Funding
Funding for this research was provided by:
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (32003B_185111)
Mind Medicine
University of Basel
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Article History
Accepted: 22 June 2025
First Online: 14 July 2025
Declarations
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: Open access funding provided by University of Basel. This work was supported by the Swiss National Science Foundation (grant no. 32003B_185111 to MEL), University Hospital Basel, and Mind Medicine, Inc. The expertise and data associated with this work and owned by the University Hospital Basel were licensed by Mind Medicine, Inc. Mind Medicine, Inc., had no role in planning or conducting the present study or writing the present publication.
: Matthias E. Liechti is a consultant for Mind Medicine, Inc. Lorenz Mueller, Aaron Klaiber, Laura Ley, Anna M. Becker, Jan Thomann, Dino Luethi, and Yasmin Schmid have no conflicts of interest that are directly relevant to the content of this article.
: Both included trials were approved by the local ethics committee (Ethikkokmmission Nordwest- und Zentralschweiz, EKNZ) and registered at ClinicalTrials.gov (NCT04227756 and NCT04849013).
: All participants provided written informed consent.
: All participants provided written informed consent.
: The datasets presented in this article are not readily available because the data associated with this work are owned by the University Hospital Basel and were licensed by Mind Medicine Inc. Requests to access the datasets should be directed to Matthias E. Liechti, matthias.liechti@usb.ch.
: Not applicable.
: YS and MEL designed the studies. LM analyzed the data. LM and AK wrote the manuscript. AK, LL, and AB performed the research. JT and DL validated the analytical method and analyzed the PK samples. All authors revised and gave final approval for the manuscript.
