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Authors
de Vries, Fenna https://orcid.org/0009-0001-3993-2898
Franssen, Eric J. F. https://orcid.org/0000-0002-1506-0730
Smit, Arthur A. J.
Moes, Dirk Jan A. R. https://orcid.org/0000-0003-3219-253X
van der Wekken, Anthonie J. https://orcid.org/0000-0001-7175-0026
Munnink, Thijs Oude https://orcid.org/0000-0001-8392-5858
Hendrikx, Jeroen J. M. A. https://orcid.org/0000-0001-8201-6599
Dumoulin, Daphne W. https://orcid.org/0000-0001-5578-7902
Koolen, Stijn L. W. https://orcid.org/0000-0002-0973-7530
Kievit, Wietske https://orcid.org/0000-0002-3984-1769
van den Heuvel, Michel M. https://orcid.org/0000-0002-6372-2153
ter Heine, Rob https://orcid.org/0000-0003-2185-8201
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Article History
Accepted: 14 July 2025
First Online: 25 July 2025
Declarations
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: Financial interest: A.v.d.W. has relationships with AstraZeneca, Boehringer Ingelheim GmbH, Pfizer Inc, F. Hoffmann-La Roche Ltd, Takeda Oncology, Bristol Myers Squibb Co., and Eli Lilly and Company, involving consulting, advisory roles, funding grants, and speaking fees. D.D. has consulting and speaking engagements with Bristol Myers Squibb Co., Merck & Co. Inc., AstraZeneca, Roche, and Pfizer. M.v.d.H. received financial support from the Radboudumc Department of Respiratory Diseases. The parties of interest had no role in the study’s design, data collection, analysis, interpretation, manuscript writing, or the decision to publish. Non-financial interest: A.v.d.W. holds a fiduciary role on the board of the ROS1ders advocacy group. R.t.H. is affiliated with Radboud University Medical Center. The parties of interest had no role in the study’s design, data collection, analysis, interpretation, manuscript writing, or the decision to publish. Editorial Board membership: D.M. is an editorial board member of Clinical Pharmacokinetics. D.M. was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. No interest: The remaining authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.
: Not applicable.
: Not applicable.
: Not applicable.
: The population pharmacokinetic model code is included as Supplementary Information.
: No funds, grants, or other support was received.
: Data is included as Supplementary Information.
: F. de Vries: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Validation, Writing—original draft. E.J.F. Franssen: Conceptualization, Supervision, Resources, Writing—review and editing. A.A.J. Smit: Conceptualization, Writing—review and editing. D.J.A.R. Moes: Writing—review and editing. A.J. van der Wekken: Writing—review and editing. T. Oude Munnink: Writing—review and editing. J.J.M.A. Hendrix: Writing—review and editing. D.W. Dumoulin: Writing—review and editing. S.L.W. Koolen: Writing—review and editing. W. Kievit: Methodology, Writing—review and editing. M.M. van den Heuvel: Conceptualization, Writing—review and editing. R. ter Heine: Conceptualization, Methodology, Supervision, Resources, Writing—original draft. All authors have provided their formal approval for this submission.
