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Authors
Van Neste, Martje
Macente, Julia
Nauwelaerts, Nina
Ameye, Lieveke
Bogaerts, Annick
Smits, Anne
Annaert, Pieter
Allegaert, Karel https://orcid.org/0000-0001-9921-5105
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Funding
Funding for this research was provided by:
Research Foundation-Flanders (18E2H24N, 1S50721N)
Innovative Medicines Initiative (821520)
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Article History
Received: 30 May 2025
Accepted: 15 September 2025
First Online: 7 November 2025
Declarations
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: NN is currently affiliated with ESQlabs GmBH. PA is founder and co-owner of BioNotus CommV. Karel Allegaert is an editorial board member of Clinical Pharmacokinetics and was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
: Data will be shared upon reasonable request.
: No ethics approval was warranted as data from Kind & Gezin were based on database research collecting data as part of routine care for quality control.
: Not applicable.
: Not applicable.
: Code for RStudio can be accessed by contacting the corresponding author and will be made available upon reasonable request.
: Conceptualisation: MVN, AS, PA, and KA. Data curation: MVN. Collection of Flemish data: LA and AB. Writing – original draft preparation: MVN and KA. Writing—review and editing: MVN, JM, NN, LA, AB, AS, PA, and KA.
