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Authors
García-Orueta, Gastón
Butragueño-Laiseca, Laura
Santiago, María José
Parra-Guillén, Zinnia P.
Trocóniz, Iñaki F. https://orcid.org/0000-0003-3700-8658
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Funding
Funding for this research was provided by:
Universidad de Navarra
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Article History
Received: 21 May 2025
Accepted: 9 November 2025
First Online: 29 November 2025
Declarations
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: No clinical data or human/animal subjects were involved in the present investigation.
: Not applicable.
: Not applicable.
: No clinical data were used to develop the current investigation. All relevant model details were obtained from publicly available sources [ – ].
: An example of the NONMEM design optimization code is provided in Supplementary material. Additional code is available from the corresponding author on reasonable request.
: GG-O, ZP-G, and IFT were responsible for the design of the study and data analysis. GG-O, LB-L, MJS, ZP-G, and IFT participated in the interpretation of the results, manuscript writing and manuscript revision.
: All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.
