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Authors
Sy, Sherwin K. B. https://orcid.org/0000-0001-6405-9130
Yoon, Deok Yong
Yang, Yiqun
Darstein, Christelle
Dasgupta, Kohinoor
Kapoor, Shruti
Wu, Shengyuan
Kawakita, Yasunori
Hoch, Matthias
Grosch, Kai
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Article History
Received: 3 August 2025
Accepted: 23 December 2025
First Online: 11 February 2026
Declarations
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: All authors are employees of Novartis. SKBS, CD, KD, SK MH, and KG own Novartis shares.
: This analysis was based on data from patients enrolled in four different trials. All four trials, serving as data sources for this analysis, were approved by the appropriate Institutional Review Board.
: Not applicable.
: Not applicable.
: All authors contributed to the study conceptualization. Data acquisition and analyses were performed by SKBS, DYY, YY, and CD. The first draft of the manuscript was written by SBKS and all authors contributed to the revision of the draft manuscript.
: Anonymized patient-level data from clinical trials may be shared by Novartis in a consortium called ClinicalStudyDataRequest.com (CSDR) in accordance with Novartis’ policy for sharing clinical trial data ( ).
: Not applicable.
