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Article History

Accepted: 4 November 2022

First Online: 6 December 2022

Declarations

:

: The study and its open access publication was funded by National Institutes of Health (US) (Grant nos. P30 CA008748, 5R01CA245499).

: JAW has received research funding from the American Society of Clinical Oncology. AAB has received research funding from The Pew Charitable Trusts, Pershing Square Sohn Cancer Research Alliances, Joe W. and Dorothy Dorsett Brown Foundation, W.M. Keck Foundation, American Brain Tumor Association, Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center, AACR, National Institutes of Health, STARR Cancer Consortium, MSKCC Center for Experimental Therapeutics, FM Kirby Foundation. AAB holds an unpaid position on the Scientific Advisory Board for Evren Scientific. AAB is an inventor on the following patents: 62/258,044, 10/413,522, and 63/052,139.

: Not applicable.

: Not applicable.

: Not applicable.

: No datasets were generated or analyzed during the current study.

: Not applicable.

: JAW and AAB both contributed to manuscript conceptualization. JAW performed the literature search, data analysis, and manuscript preparation. AAB critically revised the manuscript for intellectual content. All authors contributed substantially to the final manuscript. All authors approve the final manuscript for submission.