Jiang, Tammy http://orcid.org/0000-0002-6887-5706
Ziemssen, Tjalf http://orcid.org/0000-0001-8799-8202
Wray, Sibyl
Shen, Changyu
Söderbärg, Karin
Lewin, James B. http://orcid.org/0000-0002-2352-9113
Božin, Ivan
Freedman, Mark S. http://orcid.org/0000-0003-1255-9701
Funding for this research was provided by:
Biogen
Article History
Accepted: 5 April 2023
First Online: 8 May 2023
Declarations
:
: EVOLVE-MS-1 and the current analysis were sponsored by Biogen.
: T.J., C.S., K.S., J.B.L., and I.B. are employees of and hold stock/stock options in Biogen. T.Z. received personal compensation for consulting services and speaker honoraria from Bayer, Biogen Idec, Novartis, Sanofi, Synthon, and Teva, and financial support for research activities from Bayer, Biogen Idec, Novartis, Sanofi Aventis, and Teva. S.W. received consulting fees from and served on advisory boards for Biogen, Celgene, and EMD Serono; received research support from Biogen, Celgene, EMD Serono, Genentech-Roche, Novartis, Receptos, Sanofi-Genzyme, and TG Therapeutics; and served on speaker bureaus for Biogen, Celgene, EMD Serono, Genentech-Roche, and Sanofi-Genzyme. M.S.F. received research/educational grants from Sanofi-Genzyme; received honoraria/consultation fees from Alexion, Atara Biotherapeutics, Bayer Healthcare, Beigene, BMS (Celgene), EMD, Hoffman La-Roche, Janssen (J&J), Merck Serono, Novartis, Quanterix, Sanofi-Genzyme, and Teva Canada Innovation; served on advisory boards/boards of directors for Alexion, Atara Biotherapeutics, Bayer Healthcare, Beigene, BMS (Celgene), Celestra, Hoffman La-Roche, Janssen (J&J), McKesson, Merck Serono, Novartis, and Sanofi-Genzyme; and participated in speakers bureau for Sanofi-Genzyme and EMD Serono.
: EVOLVE-MS-1 was registered with ClinicalTrials.gov (NCT02634307). Study data will be shared in accordance with applicable regulations and laws.
: Not applicable.
: Not applicable.
: Not applicable.
: Not applicable.
: Data analysis was performed by Tammy Jiang and Ivan Bozin. The first draft of the manuscript was written by Tammy Jiang. Tammy Jiang, Tjalf Ziemssen, Sibyl Wray, Changyu Shen, Karin Söderbärg, James B. Lewin, Ivan Bozin, and Mark S. Freedman reviewed and revised drafts of the manuscript, and approved the final version.