Kreiter, Daniel http://orcid.org/0000-0003-0954-1834
Kalincik, Tomas
Hupperts, Raymond
Patti, Francesco
Spitaleri, Daniele
Foschi, Matteo
Surcinelli, Andrea
Maimone, Davide
Yamout, Bassem
Khoury, Samia J.
Lechner-Scott, Jeannette
Ozakbas, Serkan
Gerlach, Oliver
,
Barnett, M. H.
Shaw, C.
John, N. A.
Buzzard, K. A.
Skibina, O. G.
Garber, J. Y.
McCombe, P. A.
Taylor, B. V.
Van der Walt, A.
Butzkueven, H.
Grammond, P.
Grand’Maison, F.
Lapointe, E.
Sanchez-Menoyo, J. L.
Besora, S.
Lugaresi, A.
Onofrj, M.
Amato, M. P.
Alkhaboori, J.
Al-Asmi, A.
Boz, C.
Soysal, A.
Turkoglu, R.
Article History
Accepted: 30 July 2024
First Online: 6 September 2024
Declarations
:
: The MSBase Foundation is a not-for-profit organization that receives support from Biogen, Novartis, Merck, Roche, Teva, and Sanofi Genzyme. This specific study did not receive any specific grant from funding agencies in the public, commercial, or non-profit sectors.
: Serkan Ozakbas has nothing to disclose. Daniel Kreiter and Oliver Gerlach received institutional research grants. Tomas Kalincik served on scientific advisory boards for MS International Federation and World Health Organization, BMS, Roche, Janssen, Sanofi Genzyme, Novartis, Merck and Biogen, steering committee for Brain Atrophy Initiative by Sanofi Genzyme, received conference travel support and/or speaker honoraria from WebMD Global, Eisai, Novartis, Biogen, Roche, Sanofi-Genzyme, Teva, BioCSL and Merck and received research or educational event support from Biogen, Novartis, Genzyme, Roche, Celgene and Merck. Tomas Kalincik is also an Editorial Board member of CNS Drugs. He was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Raymond Hupperts received institutional research grants and fees for lectures and advisory boards from Biogen, Merck and Genzyme-Sanofi. Francesco Patti received personal compensation for serving on advisory board for Almirall, Alexion, Biogen, Bristol, Berck, Novartis and Roche. He further received research grants by Biogen, Merck and Roche and by FISM, Reload Association (Onlus), Italian Health Minister, University of Catania. Daniele Spitaleri received honoraria as a consultant on scientific advisory boards by Bayer-Schering, Novartis and Sanofi-Aventis and compensation for travel from Novartis, Biogen, Sanofi Aventis, Teva and Merck. Matteo Foschi received travel and meeting attendance support from Novartis, Biogen, Roche, Sanofi-Genzyme and Merck. Davide Maimone received speaker honoraria for Advisory Board and travel grants from Almirall, Biogen, Merck, Novartis, Roche, Sanofi-Genzyme, and Teva. Bassem Yamout received honoraria as a speaker and member of scientific advisory boards from Sanofi, Bayer, Biogen, Merck, Janssen, Novartis, Roche and Aspen. Samia J. Khoury received compensation for scientific advisory board activity from Merck and Roche and received compensation for serving on the IDMC for Biogen. Jeannette Lechner-Scott travel compensation from Novartis, Biogen, Roche and Merck. Her institution receives the honoraria for talks and advisory board commitment as well as research grants from Biogen, Merck, Roche, TEVA and Novartis.
: Ethical approval for the MSBase registry was granted by the Melbourne Health Human Research Ethics Committee and institutional review boards at each site (or exemptions were granted according to local regulations).
: All patients provided informed consent as per local institutional regulations for inclusion of their data in the registry for clinical and research purposes.
: Not applicable
: Data were obtained from the international MSBase registry. Information on data access and availability can be found on the .
: All code for data preparation and analysis can be found on .
: Daniel Kreiter: Conceptualization, Methodology, Formal analysis, Visualization, Writing—Original Draft; Tomas Kalincik: Conceptualization, Methodology, Writing—Review & Editing; Raymond Hupperts: Supervision, Conceptualization, Writing—Review & Editing; Francesco Patti: Writing—Review & Editing, Data Curation; Daniele Spitaleri: Writing—Review & Editing, Data Curation, Matteo Foschi: Writing—Review & Editing, Data Curation; Andrea Surcinelli: Writing—Review & Editing, Data Curation; Davide Maimone: Writing—Review & Editing, Data Curation; Bassem Yamout: Writing—Review & Editing, Data Curation; Samia J. Khoury: Writing—Review & Editing, Data Curation; Jeannette Lechner-Scott: Writing—Review & Editing, Data Curation; Serkan Ozakbas<sup>:</sup> Writing—Review & Editing, Data Curation; Oliver Gerlach: Supervision, Conceptualization, Writing—Review & Editing, Data Curation. All authors had authority over manuscript preparation and the decision to submit this manuscript for publication.