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Article History

Accepted: 4 November 2024

First Online: 5 December 2024

Declarations

:

: Open Access funding enabled and organized by Projekt DEAL.

: Yulia Novitskaya received lecture fees from Eisai. Andreas Schulze-Bonhage received honoraria for lectures or consulting fees from Angelini Pharma, Bial, Desitin, Eisai, GW Pharmaceuticals, JAZZ Pharma, and UCB Pharma outside the submitted work. Elisa Schütz received honoraria for lectures and support for attending one congress from Angelini Pharma, outside of the present work. Martin Hirsch received lecture fees and consulting fees from UCB, Liva Nova, Precisis AG, Bial, Eisai and Angelini Pharma outside of the present work.

: Approval was obtained from the ethics committee of University of Freiburg, Germany (reference number 21-1505). The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

: Written informed consent was obtained from participants or their legal guardian to participate in the study.

: Not applicable.

: The dataset generated and analyzed during the current study is not publicly available due to restrictions in sharing patients’ data according to the European Data Protection Regulation.

: Not applicable.

: Yulia Novitskaya: data collection, analysis and interpretation of results, visualization, writing—original draft. Andreas Schulze-Bonhage: conceptualization, writing—review & editing. Elisa Schütz: data collection, writing—review & editing. Martin Hirsch: conceptualization, methodology, data collection, writing – review & editing, supervision. All authors have read and approved the final submitted manuscript, and agree to be accountable for the work.