Document is current

Article History

Accepted: 8 June 2025

First Online: 7 August 2025

Declarations

:

: This post hoc analysis and open access fees for this publication were funded by Jazz Pharmaceuticals, Inc.

: N.S., S.A., L.L., and S.M.Z. have received consulting fees, conducted studies funded by, or received honoraria for services provided to Jazz Pharmaceuticals, Inc.; N.S. was also supported by Italian Ministry of Health with Current Research Funds; C.N. is an employee of Jazz Pharmaceuticals, Switzerland GmbH, with stock and/or stock options in the company, and T.G. is an employee of Jazz Pharmaceuticals, Inc, with stock and/or stock options in the company.

: Not applicable.

: Not applicable.

: Not applicable.

: All relevant data are provided with the manuscript and supporting files. Jazz has established a process to review requests from qualified external researchers for data from Jazz-sponsored clinical trials in a responsible manner that includes protecting patient privacy, assurance of data security and integrity, and furthering scientific and medical innovation. Additional details on Jazz Pharmaceuticals data sharing criteria and process for requesting access can be found at: .

: Not applicable.

: All authors met the International Committee of Medical Journal Editors (ICMJE) authorship criteria and had full access to relevant data. Neither honoraria nor payments were made for authorship. All authors provided substantial contributions to the conception or design of the work or the acquisition, analysis, or interpretation of data for the work; drafted the work or revised it critically for important intellectual content; provided final approval of the version to be published; and agree to be accountable for all aspects of the work.