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Article History

Accepted: 17 June 2025

First Online: 10 July 2025

Declarations

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: Not applicable.

: Nicolas Phielipp MD has received research grants from AskBio. Claire Henchcliffe MD DPhil reports the following conflicts of interest: payments as a consultant for: Abbvie; Guidepoint Global; for participation in scientific advisory boards for: AskBio; Bayer AG; Canary Global, Inc.; Certara; Johnson and Johnson; ProJenX; payment for a lecture from Vertex; payment for serving as a DSMB member for MeiraGTx; and stock options for membership of the Scientific Advisory Board of Axent Biosciences.

: Data sharing is not applicable to this article as no datasets were generated or analyzed for this study.

: Not applicable.

: Not applicable.

: Not applicable.

: Not applicable.

: Nicolas Phielipp was responsible for conception and study design; collecting data; and writing and revising the manuscript. Claire Henchcliffe was responsible for conception and study design; collecting data; and writing and revising the manuscript. Nicolas Phielipp and Claire Henchcliffe confirm that they have both read and approved the final version of the manuscript and agree to be accountable for the work.