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Article History

First Online: 26 August 2020

Declarations

:

: ER, ID, and EP are supported by institutional research funds (Ricerca Fondamentale Orientata). The study was not funded in whole or in part by any research grant or funding body.

: ID reports minor speaker fees from Bayer, Boehringer Ingelheim, Daiichi Sankyo, and Pfizer, outside the submitted work. All other authors have no conflicts of interest that are directly relevant to the content of this article.

: Not applicable.

: Not applicable.

: Not applicable.

: Data supporting the findings of this study were derived from the following resource, available in the public domain: .

: Codes for the analyses can be made available by the authors upon reasonable request.

: ER made substantial contributions to study conception and design. MF made substantial contributions to the acquisition and analysis of data. ER, MF, ID, and EP made substantial contributions to the study design and interpretation of data. ER drafted the manuscript. All authors revised the manuscript critically for important intellectual content and approved the final version.