Natsiavas, Pantelis https://orcid.org/0000-0002-4061-9815
Nikolaidis, George https://orcid.org/0000-0002-2380-9959
Pliatsika, Jenny https://orcid.org/0000-0002-2584-2541
Chytas, Achilles https://orcid.org/0000-0001-8486-011X
Giannios, George https://orcid.org/0009-0004-9385-1855
Karanikas, Haralampos https://orcid.org/0000-0002-2582-5899
Grammatikopoulou, Margarita https://orcid.org/0000-0003-1064-9439
Zachariadou, Martha https://orcid.org/0000-0001-7469-156X
Dimitriadis, Vlasios https://orcid.org/0000-0003-2544-8728
Nikolopoulos, Spiros https://orcid.org/0000-0002-1367-5133
Kompatsiaris, Ioannis https://orcid.org/0000-0001-6447-9020
Funding for this research was provided by:
European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH – CREATE - INNOVATE (Τ2EDK-00640)
Article History
Accepted: 3 June 2024
First Online: 20 July 2024
Declarations
:
: This research has been co-financed by the European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship and Innovation, under the title RESEARCH–CREATE–INNOVATE (project code: Τ2EDK-00640).
: Some of the authors (GN, JP, MZ) work for ErgoByte SA, which is a commercial company and Galinos.gr is one of its commercial products. PN is an Editorial Board member of Drug Safety. PN was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions.
: The detailed data regarding the conclusions of this paper could be available upon reasonable request. Please contact Pantelis Natsiavas (<u>pnatsiavas@certh.gr</u>) for such requests.
: The system’s source code is not available as a whole due to complex legal issues. However, parts of the code used are available in github at: . Furthermore, a demonstration of the system and the relevant code could be arranged upon reasonable request. Please contact George Nikolaidis (<u>gnikolaidis@ergobyte.gr</u>) for relevant requests.
: The Ethics Committee of the Centre for Research and Technology Hellas was informed on all activities and approved the study protocol (reference number 015577).
: All methods presented were carried out in accordance with relevant guidelines and regulations. All participants were provided with adequate information on the project, its goals and the evaluation phases and participated voluntarily, while informed consent was obtained from all participants.
: Written consent was acquired from all the study participants, who agreed to the publication of the results of this study.
: PN, GN, HK, and IK had significant contribution in the original design of the project. PN and GN designed the knowledge base and the architecture of the system. GN was the lead software developer of the PrescIT platform. JP contributed in code authoring. AC and GG constructed the Knowledge Graphs. HK supported the therapeutic prescription protocols’ integration. MG and MZ supported project management activities and the pilot testing processes. VD contributed in terms of software development. SN was the project coordinator and IK was the principal investigator. PN led the manuscript authoring process. All the authors contributed to authoring and approved the final version of the manuscript.