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Article History

Received: 9 May 2026

Accepted: 24 August 2026

First Online: 17 September 2026

Declarations

Competing interests: The author declares no financial competing interests. For transparency, the author was a coauthor of one empirical precedent cited in this review [ ]. That study is presented as an illustrative preclinical precedent and not as independent clinical, epidemiological, or causal validation. No other relevant non-financial competing interests are declared.

Author contributions: Yoshihiro Uesawa: Conceptualization, methodology, literature interpretation, writing—original draft, writing—review and editing, supervision, and final approval of the manuscript.

Ethics approval: Not applicable. This article is a narrative methodological review and does not involve human participants, animals, or identifiable personal data.

Consent to participate: Not applicable.

Consent to publish: Not applicable.

Data availability: Data sharing is not applicable to this article because no new datasets were generated or analyzed.

Code availability: Not applicable.