Boosman, René J. http://orcid.org/0000-0002-6399-2604
Burgers, Jacobus A.
Smit, Egbert F.
Steeghs, Neeltje
van der Wekken, Anthonie J.
Beijnen, Jos H.
Huitema, Alwin D. R.
ter Heine, Rob
Article History
Accepted: 22 November 2021
First Online: 11 December 2021
Declarations
:
: No external funding was used in the preparation of this manuscript.
: RJ Boosman, EF Smit, ADR Huitema, and R ter Heine have no conflicts of interest that might be relevant to the contents of this manuscript. JA Burgers is a member of advisory boards for Roche and BMS and has received support from MSD for an investigator-initiated study. All of these conflicts are outside of the submitted work, and any reimbursement was paid to their institution. N Steeghs has provided consultation or attended advisory boards for AIMM Therapeutics, Boehringer Ingelheim, and Ellipses Pharma; has received research grants for the institute from AB Science, Abbvie, Actuate Therapeutics, Amgen, Array, AstraZeneca/MedImmune, Bayer, Blueprint Medicines, Boehringer Ingelheim, Bristol-Myers Squibb, Cantargia, CellCentric, Cytovation, Deciphera, Genentech/Roche, GlaxoSmithKline, Incyte, Lilly, Merck Sharp & Dohme, Merus, Molecular Partners, Novartis, Pfizer, Pierre Fabre, Roche, Sanofi, Taiho, and Takeda. All of these conflicts are outside of the submitted work, and any reimbursement was paid to their institution. AJ van der Wekken has received grants from AstraZeneca, Boehringer Ingelheim, Pfizer, Roche, and Takeda; has received payment for lectures from Pfizer, Boehringer Ingelheim, and Takeda; and is a member of the advisory boards of Boehringer Ingelheim, Takeda, and Janssen. All of these are outside of the submitted work. JH Beijnen has received payment for expert testimony for Hoyng Tokh Monegier (paid to their institution), is a part-time employee and (in)direct stockholder of Modra Pharmaceuticals and (jointly) holds a patent on oral taxane formulations clinically developed by Modra Pharmaceuticals. Modra Pharmaceuticals is a small spin-off company of the Netherlands Cancer Institute. All of these conflicts are outside of the submitted work.
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: RJ Boosman: conceptualization, methodology, investigation, writing original draft. JA Burgers, EF Smit, N Steeghs: conceptualization, methodology, writing review and editing. AJ van der Wekken: writing review and editing. JH Beijnen: writing review and editing. ADR Huitema: conceptualization, methodology, writing review and editing, supervision. R ter Heine: conceptualization, methodology, writing review and editing, and supervision.