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Article History

Accepted: 21 August 2024

First Online: 23 September 2024

Declarations

:

: his work was supported by the National Natural Science Foundation of China [Major Joint Project: U21A20355]; the national key research and development plan of China, major project of prevention and treatment for common diseases [2022YFC2505300, sub-project: 2022YFC2505302]; the National Natural Science Foundation of China [82270878, 81970720, 82170825]; Joint Medical Research Project of Chongqing Science and Technology Commission and Chongqing Health and Family Planning Commission [Major Project, 2022ZDXM003]; Chongqing Outstanding Youth Funds [CSTB2023NSCQ-JQX0028]; Program for Youth Innovation in Future Medicine, Chongqing Medical University [Jinbo Hu and Rufei Gao]; Program for Major Scientific and Technological Talents, Chongqing Medical University [Jinbo Hu and Shumin Yang].

: Xiaoyan Yi, Shumin Yang, Jun Yang, Xiangjun Chen, Aiping Zhang, Qinglian Zeng, Wenjin Luo, Qifu Li, and Jinbo Hu declare that they have no potential conflicts of interest that might be relevant to the contents of this article.

: XY, SY, QL, and JH conceived of and designed the study. XY, SY, and WL did the analysis. XY and SY drafted the manuscript. XY, SY, JY, AZ, QL, and JH revised and edited the manuscript. All authors had full access to and verified the data, and had final responsibility for the decision to submit for publication.

: All the data collected for the study, study protocol, and statistical code are available to approved persons through written agreements with the authors and the data partner with publication from QL (e-mail: liqifu@yeah.net) or JH (email: hujinbo@cqmu.edu.cn).

: Not applicable.

: Not applicable.

: Not applicable.

: Not applicable.