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Article History

Received: 11 July 2025

Accepted: 19 November 2025

First Online: 3 February 2026

Declarations

:

: Herbert S.B. Baraf: Arthrosi, Olatec, Sobi, Otsuka, Pacira. Naomi Schlesinger: Amgen, Arthrosi, Novartis, Olatec, Protalix, Shanton, Sobi, Scilex, Avalo. Vibeke Strand: AbbVie, Alpine, Alumis, Amgen, AstraZenecaBayer, Blackrock, BMS, Boehringer Ingelheim, Celltrion, Citryll, Contura, Fortress Biotech, Genentech/Roche, GSK, Inmedix, Janssen, Kiniksa, Lilly, Novartis, Omeros, Pfizer, RAPT, Regeneron, R-Pharm, Samsung, Sandoz, Sanofi, Scipher, Setpoint, Sobi, Spherix, Synact, Takeda, Urica, Vertex.

: This extended review presents information from phase I–III clinical studies of NASP. All study protocols were approved by an ethics committee or institutional review board at each participating center.

: Not applicable.

: Not applicable.

: The datasets analyzed during the current study are available from the corresponding author on reasonable request. Sobi is committed to responsible and ethical sharing of data on the participant-level and summary data for medicines and indications approved by the European Medicines Agency and/or FDA, while protecting individual participant integrity and compliance with applicable legislation. Data access will be granted in response to qualified research requests. All requests are evaluated by a cross‐functional panel of experts within Sobi, and a decision on sharing will be based on the scientific merit and feasibility of the research proposal, maintenance of personal integrity, and commitment to publication of the results. To request access to study data, a data-sharing request form (available on ) should be sent to medical.info@sobi.com. Further information on Sobi’s data sharing policy and process for requesting access can be found at: .

: Not applicable.

: All authors meet the International Committee of Medical Journal Editors’ criteria for authorship for this article. All authors were responsible for manuscript conceptualization, writing the original draft, and reviewing and editing the final manuscript draft. All authors take responsibility for the manuscript as a whole and have given their approval for this version to be published.