Heinrich, Maria http://orcid.org/0000-0002-4530-7343
Müller, Anika http://orcid.org/0000-0002-6859-7080
Cvijan, Andela
Mörgeli, Rudolf http://orcid.org/0000-0001-8506-5898
Kruppa, Jochen http://orcid.org/0000-0001-8376-8864
Winterer, Georg http://orcid.org/0000-0002-3610-5029
Slooter, Arjen J. C. http://orcid.org/0000-0003-0804-8378
Spies, Claudia D. http://orcid.org/0000-0002-1062-0495
,
Clinical trials referenced in this document:
Documents that mention this clinical trial
Stability of neuropsychological test performance in older adults serving as normative controls for a study on postoperative cognitive dysfunction
https://doi.org/10.1186/s13104-020-4919-3
Preoperative thalamus volume is not associated with preoperative cognitive impairment (preCI) or postoperative cognitive dysfunction (POCD)
https://doi.org/10.1038/s41598-023-38673-x
Preoperative Comparison of Three Anticholinergic Drug Scales in Older Adult Patients and Development of Postoperative Delirium: A Prospective Observational Study
https://doi.org/10.1007/s40266-021-00839-5
Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients
https://doi.org/10.1186/s12920-021-01071-1
Funding for this research was provided by:
Seventh Framework Programme (n. 602461)
Charité
Article History
Accepted: 28 January 2021
First Online: 15 March 2021
Change Date: 18 May 2021
Change Type: Update
Change Details: Brief wording: The Funding note is included in the Acknowledgement section and deleted from the Declarations section.
Declarations
:
: Maria Heinrich is a participant in the Charité Digital Clinician Scientist Program funded by Deutsche Forschungsgemeinschaft. Maria Heinrich, Anika Müller, Andela Cvijan, Rudolf Mörgeli, Jochen Kruppa, Georg Winterer, Arjen J. C. Slooter and Claudia D. Spies have no conflicts of interest that are directly relevant to the content of this article.
: This was a prospective multicenter observational study conducted at the clinical study centers Charité-Universitätsmedizin Berlin, Department of Anesthesiology and Operative Intensive Care Medicine, Berlin, Germany, and the University Medical Center Utrecht, Department of Intensive Care Medicine, Utrecht, Netherlands. The study was approved by the local Ethics Committees (ref.: EA2/092/14 and 14-469) and conducted in accordance with the declaration of Helsinki (ClinicalTrials.gov: NCT02265263).
: Written informed consent was obtained from each patient, and all local data privacy regulations were followed.
: Written informed consent was obtained from each patient.
: The datasets generated and analyzed during the current study are not publicly available as no consent for this was obtained from participants but are available from the corresponding author on reasonable request.
: Not applicable.
: Maria Heinrich, Anika Müller, and Rudolf Mörgeli were involved in data collection and plausibility checks. Maria Heinrich, Anika Müller, and Claudia Spies developed the research question. Maria Heinrich and Jochen Kruppa carried out the analyses. The first draft of the manuscript was written by Maria Heinrich, and all authors commented on subsequent versions and read and approved the final manuscript. Georg Winterer, Arjen Slooter, and Claudia Spies designed and directed the BioCog project.