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Article History

Accepted: 15 February 2022

First Online: 9 March 2022

Declarations

:

: CEA was supported by an Early Postdoc.Mobility grant from the Swiss National Science Foundation (Grant P2LAP3_184042), and JD was funded by the Swiss National Science Foundation. This work is part of the ‘OPERAM: OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly’ project supported by the European Union’s Horizon 2020 research and innovation programme under Grant agreement no. 6342388, and by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 15.0137. The OPERAM study is also funded by the Swiss National Scientific Foundation (SNSF 320030_188549). The opinions expressed and arguments employed herein are those of the authors and do not necessarily reflect the official views of the European Commission and the Swiss government. The funders had no roles in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Open access funding provided by University of Bern.

: Carole E. Aubert, Nicolas Rodondi, Samuel W. Terman, Martin Feller, Claudio Schneider, Jolanda Oberle, Olivia Dalleur, Wilma Knol, Denis O’Mahony, Drahomir Aujesky, and Jacques Donzé declare that they have no conflicts of interest.

: The original data from the trial cannot be made available but the codes are available upon reasonable request.

: Conception of the project: CEA, NR, JD. Data collection: NR, DOM, OD, WK, JO. Data analysis and interpretation: CEA, JD, SWT. Drafting of the manuscript: CEA. Critical revision of the manuscript: All authors.

: The OPERAM trial was approved by all local Ethics Committees. No additional approval was requested for this subanalysis.

: All authors approved the current manuscript for publication.