Sibille, François-Xavier http://orcid.org/0000-0003-4173-8581
de Saint-Hubert, Marie
Henrard, Séverine
Aubert, Carole Elodie
Goto, Namiko Anna
Jennings, Emma
Dalleur, Olivia
Rodondi, Nicolas
Knol, Wilma
O’Mahony, Denis
Schwenkglenks, Matthias
Spinewine, Anne
Clinical trials referenced in this document:
Documents that mention this clinical trial
Benzodiazepine Receptor Agonists Use and Cessation Among Multimorbid Older Adults with Polypharmacy: Secondary Analysis from the OPERAM Trial
https://doi.org/10.1007/s40266-023-01029-1
Frequency and Acceptance of Clinical Decision Support System-Generated STOPP/START Signals for Hospitalised Older Patients with Polypharmacy and Multimorbidity
https://doi.org/10.1007/s40266-021-00904-z
Hospital physicians’ and older patients’ agreement with individualised STOPP/START-based medication optimisation recommendations in a clinical trial setting
https://doi.org/10.1007/s41999-022-00633-5
Rationale and design of OPtimising thERapy to prevent Avoidable hospital
admissions in Multimorbid older people (OPERAM): a cluster randomised
controlled trial
https://doi.org/10.1136/bmjopen-2018-026769
Optimizing Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older Adults (OPERAM): cluster randomised controlled trial
https://doi.org/10.1136/bmj.n1585
Funding for this research was provided by:
Fonds De La Recherche Scientifique—FNRS (Clinical Master Specialist Applicant for a Ph.D)
Swiss National Science Foundation (SNSF 320030_188549, 325130_204361)
Horizon 2020 (634238)
Article History
Accepted: 4 April 2023
First Online: 23 May 2023
Declarations
:
: This work is part of the project “OPERAM: OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly” supported by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 634238, and by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 15.0137. The OPERAM project was also partially funded by the Swiss National Scientific Foundation (SNSF 320030_188549 and 325130_204361). François-Xavier Sibille is a Clinical Master Specialist Applicant for a Ph.D. of the Fonds de la Recherche Scientifique—FNRS. The opinions expressed herein are those of the authors and do not necessarily reflect the official views of the funders. The funders had no role in the study design; data collection, analysis, and interpretation; or writing of the report. Open access funding was provided by UCLouvain and CHU UCL Namur.
: François-Xavier Sibille is a Clinical Master Specialist Applicant for a Ph.D. of the Fonds de la Recherche Scientifique—FNRS. The funder had no role in study design, data collection, data analysis, data interpretation, or writing of the report. All other authors declare that they have no conflict of interest.
: The datasets analyzed during the current study will be made available on reasonable request. Data will be made available for scientific purposes for researchers whose proposed use of the data has been approved by the OPERAM publication committee.
: The OPERAM trial was approved by the independent research ethics committees at each participating site (lead ethics committee: Cantonal Ethics Committee Bern, Switzerland, ID 2016-01200; Medical Research Ethics Committee Utrecht, the Netherlands, ID 15-522/D; Comité d’Ethique Hospitalo-Facultaire Saint-Luc-UCL: 2016/20JUL/347–Belgian registration No: B403201629175; Cork University Teaching Hospitals Clinical Ethics Committee, Cork, Republic of Ireland; ID ECM 4 [o] 07/02/17), and Swissmedic as the responsible regulatory authority. The authors certify that the study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
: Written informed consent was obtained from the participants or their legal representatives before enrollment in the OPERAM trial.
: Not applicable.
: The codes used during the current study will be made available on reasonable request.
: Authorship eligibility is based on the International Committee of Medical Journal Editors (ICMJE) authorship criteria. The authors certify that they have participated in the following aspects: conception and design (all authors); acquisition and interpretation of data (FXS, MdSH, SH, AS); drafting the article (FXS, MdSH, AS) and revising it critically for important intellectual content (all authors). All authors have approved the final article, and agree to be accountable for the work.