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Article History

Accepted: 10 July 2025

First Online: 2 August 2025

Declarations

:

: This work was supported by the Doctor Training and Promotion Project of Xijing Hospital (XJZT24LY39), the Clinical Research Project of Air Force Medical University (2022LC2208), the Key Industrial Innovation Chain Project of Shaanxi Province Key Research and Development Plan (2024SF-YBXM-004), the General Project of Shaanxi Province Key Research and Development Plan (2024GX-YBXM-136), the Medical and health scientific research guidance project of Qingdao (2023-WJZD244).

: Shuai Zhao, Boda Zhu, Yan Chen, Tiantong Yu, Bohui Zhang, Xi Zhang, Peng Han, Youhu Chen, Genrui Chen, Li Yang, Zhijun Tan, Gang Wang, Sida Jin, Yi Yang, Rutao Wang, Chengxiang Li, and Kun Lian declare that they have no potential conflicts of interest that might be relevant to the contents of this manuscript.

: The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

: The study was approved by the Ethics Committee of Xijing Hospital, the Fourth Military Medical University, (KY20202042-C-1). CODE AVAILABILITY: Not applicable.

: Each subject was provided with informed consent before recruitment.

: Not applicable.

: The conception and design of the study and manuscript drafting were performed by Shuai Zhao, Boda Zhu, Yan Chen, Rutao Wang, Chengxiang Li, and Kun Lian. The generation and data collection and follow-up were performed by Tiantong Yu, Bohui Zhang, Xi Zhang, Peng Han, Youhu Chen andGenrui Chen. The assembly and analysis and/or interpretation of the data were performed by Li Yang, Zhijun Tan, Gang Wang, Sida Jin and Yi Yang. All authors read and approved the final manuscript.