Mulherin, Brian P. http://orcid.org/0009-0001-3959-3013
Yeh, Michael
Al-Adhami, Mohammed
Dingli, David
Clinical trials referenced in this document:
Documents that mention this clinical trial
Normalization of Hemoglobin, Lactate Dehydrogenase, and Fatigue in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Pegcetacoplan
https://doi.org/10.1007/s40268-024-00463-9
Documents that mention this clinical trial
Comparative Effectiveness of Pegcetacoplan Versus Ravulizumab and Eculizumab in Complement Inhibitor-Naïve Patients with Paroxysmal Nocturnal Hemoglobinuria: A Matching-Adjusted Indirect Comparison
https://doi.org/10.1007/s12325-023-02438-9
Normalization of Hemoglobin, Lactate Dehydrogenase, and Fatigue in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Pegcetacoplan
https://doi.org/10.1007/s40268-024-00463-9
Funding for this research was provided by:
Apellis Pharmaceuticals
Swedish Orphan Biovitrum
Article History
Accepted: 17 April 2024
First Online: 10 May 2024
Declarations
:
: This study was sponsored by Apellis Pharmaceuticals, Inc., and Swedish Orphan Biovitrum AB. The sponsors also contributed to data interpretation and manuscript development. Writing assistance was funded by Apellis Pharmaceuticals, Inc., and Swedish Orphan Biovitrum AB.
: Brian P. Mulherin has no disclosures to declare. Michael Yeh is an employee of Apellis and holds stock options. Mohammed Al-Adhami was an employee of Apellis at the time of the study. David Dingli serves on advisory boards with compensation from Alexion (AstraZeneca), Apellis, Janssen, Novartis, and Sanofi; and receives research support from K-36 Therapeutics.
: Original study protocols were designed and monitored in accordance with the ethical principles of Good Clinical Practice and the Declaration of Helsinki, and approved by an Institutional Review Board or independent Ethics Committee at each center.
: Patients provided written informed consent before the initiation of study-related procedures.
: Participants consented to publication provided their confidentiality would be maintained, which it is in the data reported in this manuscript.
: The datasets generated and/or analyzed during the current study are not publicly available but are available from the corresponding author on reasonable request.
: Not applicable.
: All authors contributed to the conception and design of this analysis, the interpretation of data, and the critical revision of the manuscript; agree to be accountable for ensuring the integrity and accuracy of the work; and approved the final version of the manuscript.