Turner, Timothy J. http://orcid.org/0000-0001-9770-2647
Brun, Pricilla
Gruber, Ross C.
Ofengeim, Dimitry
Article History
Accepted: 16 May 2024
First Online: 5 July 2024
Declarations
:
: All authors participated in the conception and design, analysis, interpretation, drafting, and final approval of the manuscript.
: Details on Sanofi’s data sharing criteria, eligible studies, and process for requesting access can be found at: .
: T.J.T., P.B., and D.O. are employees of Sanofi (may hold shares and/or stock options in the company). R.C.G. was an employee of Sanofi when this work was undertaken (may hold shares in the company).
: Sanofi.
: The Test Facility is accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) and registered with the United States Department of Agriculture (USDA) to conduct research in laboratory animals. The veterinary care of the animals was in accordance with the protocol, Test Facility’s SOPs, and regulations outlined in the applicable sections of the Final Rules of the Animal Welfare Act regulations (9 CFR), the Public Health Service Policy on Humane Care and Use of Laboratory Animals, the Guide for the Care and Use of Laboratory Animals1,2, and the Biomedical Research Models, Inc., Policy on Humane Care. The protocol and any amendments or procedures involving the care or use of animals in this study were approved by the Test Facility’s Institutional Animal Care and Use Committee (IACUC) before the initiation of such procedures. The Attending Veterinarian was responsible for implementation of programs for the evaluation of the health status of study animals, the recommendation of treatment for health conditions, the evaluation of response to treatment, as well as the diagnosis of pain or distress. The veterinary staff communicates with the Study Director signs of animal illness,injury, pain and distress, and guidance regarding treatment of the animal(s) and/or alteration of study procedures. In nonemergency situations, decisions regarding the study animals, including treatments, alterations in study design, and/or justification of no action were documented and justified, and approved in advance by the Study Director, and in consultation with Sponsor as appropriate. No software coding was performed for the project.
: Not applicable.