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Article History

Accepted: 12 May 2025

First Online: 12 July 2025

Declarations

:

: GeneScience sponsored the study.

: Tianhong Luo, Ying Ding, Xiaoyan Zhu, and Weiwei Gao are employees of GeneScience.We have fully considered the conflicts of interest policy, according to the Journal.

: The data supporting this study's findings are not openly available due to reasons of sensitivity and are available from the corresponding author upon reasonable request.

: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Shanghai General Hospital (Date 11 Nov 021/No.[2021]146).

: Informed consent was obtained from all individual participants included in the study.

: All authors read, approved the final manuscript, and consented to its publication.

: Not applicable. The study used only licensed commercial software without any custom code.

: All authors contributed to the study's conception and design. Material preparation, data collection, and analysis were performed by Jigang Zhang, Mingjian Zhang, Wenyuan Xue, Yixin Zha, Shujing Jin, Tianhong Luo, Ying Ding, Xiaoyan Zhu, Weiwei Gao, and Xueying Ding. The first draft of the manuscript was written by Jigang Zhang, and all authors commented on previous versions.