Minichmayr, Iris K. http://orcid.org/0000-0002-2679-8589
Knaack, Ursula
Gojo, Johannes http://orcid.org/0000-0002-8113-3416
Senfter, Daniel http://orcid.org/0000-0001-9203-4563
Haberler, Christine http://orcid.org/0000-0003-1016-0545
Azizi, Amedeo A. http://orcid.org/0000-0002-1347-6644
Mayr, Lisa http://orcid.org/0000-0002-6841-0749
Zeitlinger, Markus http://orcid.org/0000-0002-1873-3953
Peyrl, Andreas http://orcid.org/0000-0002-5736-8231
Funding for this research was provided by:
Forschungsgesellschaft für Cerebrale Tumore
Medical University of Vienna
Article History
Accepted: 4 March 2024
First Online: 8 April 2024
Declarations
:
: Open access funding provided by Medical University of Vienna. This study was merely supported by internal funding. AP received administrative support from <i>Forschungsgesellschaft für cerebrale Tumore</i>.
: Iris K. Minichmayr, Ursula Knaack, Johannes Gojo, Daniel Senfter, Christine Haberler, Amedeo A. Azizi, Lisa Mayr, Markus Zeitlinger, and Andreas Peyrl declare that they have no conflicts of interest that might be relevant to the contents of this article.
: Data obtained in the study are presented in the article. The datasets generated during and/or analyzed during the current study are available from the study center on reasonable request.
: The study was approved by the Ethics Committee of the Medical University of Vienna, carried out in accordance with the Declaration of Helsinki, and registered in the European Clinical Trials Database (EudraCT number 2009-013024-23).
: Written informed consent was obtained from the parents and/or the participants themselves.
: Not applicable.
: The NONMEM code was based on a previously published population pharmacokinetic model. The control stream used for the current analysis is available on reasonable request.
: IKM: Conceptualization; analysis and interpretation of data; methodology; visualization of results; writing the original draft; writing—review and editing. UK: Conceptualization; data acquisition; formal analysis; writing—review and editing. JG: Conceptualization; data curation; formal analysis; methodology; supervision; writing the original draft; writing—review and editing. DS: Data curation; formal analysis; writing—review and editing. CH: Data curation; formal analysis; writing—review and editing. AA: Conceptualization; data curation; investigation; writing—review and editing. LM: Data curation; investigation; writing—review and editing. MZ: Supervision; interpretation of results; writing—review and editing. AP: Conceptualization; data curation; investigation; project administration; supervision; validation; writing the original draft; writing—review and editing. All authors critically reviewed and approved the final version of the manuscript.