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Article History

Accepted: 27 January 2025

First Online: 21 February 2025

Declarations

:

: Dr Leonard is affiliated with the Colorado Department of Health Care Policy & Financing. The authors have disclosed no conflicts of interest concerning the research, authorship, or publication of this article. None of the authors are affiliated with or hold financial interests in the manufacturers of the gene therapies investigated in this study. The views expressed in this article represent the opinions of the authors and do not necessarily reflect those of their respective employers.

: The University of Colorado is funded by the Department of Health Care Policy & Financing for the assessment of value-based contracts.

: The study was declared exempt by the Colorado Multiple Institutional Review Board.

: Not applicable.

: Not applicable.

: All data analyzed during this work are from the Colorado Department of Health Care Policy & Financing. The data are not publicly available. The model used during this work was developed by the University of Colorado under a contract with the Colorado Department of Health Care Policy & Financing.

: Not applicable.

: Antal Zemplenyi, Brett McQueen, Jim Leonard, Michael DiStefano, Kelly Anderson, and Kavita Nair contributed to the study conception and design. Material preparation, data collection and analysis were performed by Garth Wright and Antal Zemplenyi. The first draft of the manuscript was written by Antal Zemplenyi and Brett McQueen, and all authors commented on previous versions of the manuscript. All authors read and approved the final version of the paper.