Document is current

Article History

Accepted: 28 April 2026

First Online: 22 June 2026

Declarations

:

: Begonya Nafria, Alexander Perera, Segolene Gaillard, Martine Dehlinger-Kremer, Pamela Dicks, Ricardo M. Fernandes, Gilles Vassal, Pirkko Lepola, Gunter F. Egger, Lucy Bray, Barbara E. Bierer, and Bob Phillips have no conflicts of interest that are directly relevant to the content of this article.

: The project was approved by the Ethics Committee of the Institut de Recerca Sant Joan de Déu on 9 March, 2023 (code PIC-40-23).

: Not applicable.

: Not applicable.

: The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request.

: The computer program is not available.

: Conception and design of the paper: BN; data collection: BN and AP; data curation: BN and AP; formal analysis: BN; investigation: BN; methodology: BN; writing (original draft): BN; writing (review and editing): all authors. All authors read and approved the final version of the manuscript.

: The views expressed in this article are the personal views of the authors and may not be understood or quoted as being made on behalf of or reflecting the position of the EMA or one of its committees or working parties or reflecting the position of the regulatory agency/agencies or organizations with which the authors are affiliated.